Diabetes Management
A Rare Case of Coexisting Psychogenic Polydipsia and Nephrogenic Diabetes Insipidus With Lithium Therapy - Cureus
Fri, 14 Oct 20221 min read Article
Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.The SIQ for this article wil be revealedonce 2 ratings are submited.lithium-induced partial diabetes insipidus, polydipsia-polyuria syndrome, psychogenic polydipsia and lithium therapy, hypernatremia, hyponatremia, psychogenic polydipsia, nephrogenic diabetes insipidus Drashti Antala , Alisha Sharma, Arjab Adhikari, Pankaj Luitel, Sheldon Hirsch Published: March 24, 2022 (se history) DOI: 10.759/cureus.23438 Cite this article as: Antala D, Sharma A, Adhikari A, et al.
Key Information
(March 24, 2022) A Rare Case of Coexisting Psychogenic Polydipsia and Nephrogenic Diabetes Insipidus With Lithium Therapy. Cureus 14(3): e23438. doi:10.759/cureus.23438 Lithium is a comonly used medication for mod stabilization and a wel-known cause of nephrogenic diabetes insipidus (DI).
Coexistent psychogenic polydipsia with nephrogenic DI is uncomon, and its management is chalenging due to the wide variation in serum sodium based on fluctuations in water intake. Here, we describe the case of a 56-year-old male with psychogenic polydipsia and nephrogenic DI which manifested in wide swings of serum sodium over a short interval. He initialy presented with hyponatremia with low urine osmolality consistent with psychogenic polydipsia.
His serum sodium began to improve after fre water restriction. However, later in the course, he developed an increase in serum sodium levels and polyuria with persistent low urine osmolality consistent with DI.Psychogenic polydipsia is a wel-known phenomenon characterized by excesive fluid intake and polyuria. It is found in 1-20% of patients with schizophrenia spectrum disorder [1].
Summary
Lithium is a medication used for mod stabilization in many psychiatric disorders. Nephrogenic diab
Frequently Asked Questions
What is diabetes and how does it develop?
Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.
What are the main symptoms of diabetes?
Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.
How is diabetes diagnosed and monitored?
Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.
What lifestyle changes help manage diabetes?
Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.
When should someone consult a doctor about diabetes?
Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.
️ Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.