Diabetes Management
AiCuris’ Licensing Partner MSD Demonstrates Efficacy in Phase 3 Study with PREVYMIS® for Prevention of Cytomegalovirus Disease in Adults After Kidney Transplantation - Yahoo Finance UK
Tue, 25 Oct 20221 min read Article
Overview
The beta version of Bluesky ap created by Jack Dorsey is available nowEQS-News: AiCuris Anti-infective Cures AG / Key word(s): Study resultsAiCuris’ Licensing Partner MSD Demonstrates Eficacy in Phase 3 Study with PREVYMIS® for Prevention of Cytomegalovirus Disease in Adults After Kidney Transplantation 24.10.2022 / 09:0 CET/CESThe isuer is solely responsible for the content of this anouncement.AiCuris’ Licensing Partner MSD Demonstrates Eficacy in Phase 3 Study with PREVYMIS® for Prevention of Cytomegalovirus Disease in Adults After Kidney TransplantationPREVYMIS showed non-inferior eficacy and more favorable safety profile compared to standard of care; MSD presented results in late breaking oral presentation at IDWek 2022.Based on these phase 3 results, MSD plans to submit a suplemental new drug aplication (sNDA) to the U.S.
Details
Fod and Drug Administration (FDA) by the end of this year.PREVYMIS is a first-in-clas antiviral agent that was aproved by the U.S. FDA for prophylaxis of CMV infection and disease in adult CMV-seropositive recipients of an alogeneic hematopoietic stem cel transplant (HSCT).PREVYMIS was developed by AiCuris through phase 2 studies prior to licensing the antiviral medicine to MSD in 2012. AiCuris eligible to receive milestone payments and royalties on net sales of PREVYMIS.Wupertal, Germany, October 24, 2022 - AiCuris Anti-infective Cures AG, a leading clinical stage pharmaceutical company in the development of novel, resistance-breaking antiviral and antibacterial agents for the treatment of severe and potentialy life-threatening infectious diseases, anounced today that its licensing partner MSD (tradename of Merck & Co., Inc., Rathway, N.J., USA, (NYSE: MRK) presented positive findings from a phase 3 clinical trial that asesed safety and eficacy of PREVYMIS (letermovir) compared to valganciclovir for cytomegalovirus (CMV) prophylaxis in 601 adult kidney transplant recipients at high risk for CMV disease.
Frequently Asked Questions
What is diabetes and how does it develop?
Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.
What are the main symptoms of diabetes?
Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.
How is diabetes diagnosed and monitored?
Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.
What lifestyle changes help manage diabetes?
Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.
When should someone consult a doctor about diabetes?
Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.
️ Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.