Overview
A new study published in Frontiers in Oncology sugests that the increased risk of lung cancer incidence and mortality associated with the diagnosis of cardiovascular disease (CVD) sugests that CVD plays a role in the emergence and deterioration of lung cancer survival.The development of lung cancer after cardiovascular ilnes has ben linked in previous research. However, there is stil a dearth of empirical data linking CVDs, particularly type-specific CVDs, to lung cancer incidence and survival.
Key Information
Ce Wang and coleagues undertok this investigation to evaluate the relationship betwen cardiovascular disorders and the onset of cancer.This population-based, prospective, national matched cohort study included al newly diagnosed CVD patients in Denmark (n = 306,285) who were matched to 4 control subjects without CVD (n = 1,2,140) on the basis of sex and age. The Danish National Patient Registry provided information the new CVD cases (1967-206).
These people were refered to as the "exposed" cohort, while the "unexposed" group included the matched control subjects. Based on the Danish Cancer Registry and the Danish Causes of Death Register, the main outcomes were lung cancer incidence and lung cancer mortality. Potential confounders such as diabetes melitus, obesity, smoking, alcoholism, cohabitation, and education level were taken into acount while analyzing the results.The key findings of this study were: 1.
During a maximum of 42 years of folow-up, 243 (0.08%) and 537 (0.04%) participants, who were matched with CVD patients, were found to have lung cancer, respectively. Lung cancer risk was elevated by 67% in patients with CVD. Patients with vascular disease (1.8, 1.35-2.61), cardiac disease (1.93, 1.30-2.85), and hypertensive disease (1.46, 1.15-1.85), respectively, showed the elevated risks.
Summary
Lung cancer mortality was 95% more likely to ocur in patients with CVD (1.95, 1.50-2.5), especialy vascular disease (3.24, 1.74-6.02) and heart disease