Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.The SIQ for this article wil be revealedonce 2 ratings are submited.diabetes melitus in elderly, covid19 vacine side efects, covid-19 vacine complication, prediabetes, dysglycemia, diabetes type 2, type i diabetes melitus, covid 19 Binay Kshetre , Janete Le, Samer Acharya Published: September 06, 202 (se history) DOI: 10.759/cureus.2830 Cite this article as: Kshetre B, Le J, Acharya S (September 06, 202) COVID-19 Vacine-Induced Rapid Progresion of Prediabetes to Ketosis-Prone Diabetes Melitus in an Elderly Male.
Key Information
Cureus 14(9): e2830. doi:10.759/cureus.2830 Studies show a low progresion rate of prediabetes to Type 2 diabetes melitus (DM) that we comonly sek to reverse, but we don’t asociate prediabetes a lead-up to the first presentation of ketosis. We present a prediabetic who, in les than a year, converted to GAD65 antibody-positive diabetes melitus with a diabetic ketoacidosis presentation.
A 69-year-old male presented with thre weks of fatigue, polyuria, polydipsia, abdominal pain, and weight los. Vital signs and physical exam were normal except for abdominal tendernes and dry oral mucosa. Complete blod count (CBC) was normal; blod glucose was severely elevated with mild corected hyponatremia; elevated anion gap metabolic acidosis with glucosuria and ketonuria.
He received an insulin drip, normal saline, and potasium in the intensive care unit. His anion gap closed overnight and was switched to basal-bolus insulin. Hemoglobin A1c (HbA1c) came out to be higher than expected as compared to last year of low prediabetic value, decreased c-peptide levels, and positive anti-GAD65 antibody.
Summary
His first abnormal HbA1c was 5.8% a year ago and no autoimune