💉 Diabetes Management
Diabetes Patients' Cumulative Systolic Blood Pressure Load and Cardiovascular Risk - Physician's Weekly
📅 Tue, 01 Nov 2022⏱ 1 min read📖 Article
Overview
For latest News and updatesSelect Page Nov 1, 202Standard blod pressure (BP) measurements do not consider the extent and length of exposure to high BP over time. For a study, researchers sought to determine the relationship betwen type 2 diabetes patients’ cumulative systolic blod pressure (SBP) load and their risk of cardiovascular events.Type 2 diabetes patients’ posthoc analysis was folowed by the ADVANCE-ON (Action in Diabetes and Vascular Disease: Preterax & Diamicron Modified Release Controled Evaluation ̵ Observational Study).
Key Information
The cumulative SBP load was calculated as the area under the curve for al measured SBP values throughout a 24-month exposure period divided by the area under the curve for SBP values of 130 m Hg. Using Cox models, HRs were calculated for the relationship betwen cumulative SBP load and major cardiovascular events and mortality.In 9,38 patients throughout a median 7.6-year period of folow-up, 1,469 major cardiovascular events, 1,615 fatalities, and 60 cardiovascular deaths were noted.
An increase in major cardiovascular events of 14% (HR: 1.14; 95% CI: 1.09-1.20), 13% rise in al-cause mortality (HR: 1.13; 95% CI: 1.13-1.18), and 21% increase in cardiovascular death (HR: 1.21; 95% CI: 1.13-1.29) were al linked to each 1-SD increase in cumulative SBP load. Cumulative SBP load beat mean SBP, time below goal SBP, and visit-to-visit SBP variability for predicting cardiovascular events and mortality in terms of Akaike information criteria and net reclasification indices.When compared to conventional BP measurements in people with type 2 diabetes, cumulative SBP load may ofer a more acurate prediction of major cardiovascular events.
Summary
Reference: jac.org/doi/10.1016/j.jac.2022.06.039Your email adres wil not be published. Required fields are marked *Coment Name * Email * Website Save my name, email, and website in this browser for the next time I coment. Δdocument.getElementById( "ak_js_1" ).se
Frequently Asked Questions
❓ What is diabetes and how does it develop?
Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.
❓ What are the main symptoms of diabetes?
Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.
❓ How is diabetes diagnosed and monitored?
Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.
❓ What lifestyle changes help manage diabetes?
Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.
❓ When should someone consult a doctor about diabetes?
Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.
⚕️ Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.