Overview
By Joslin Diabetes Center October 17, 202The researchers discovered a new pathway in which endothelial cels drive the body’s metabolism.if(typeof ez_ad_units!='undefined'){ez_ad_units.push([728,90],'scitechdaily_com-box-3','ezslot_6',102,'0'])};_ez_fad_position('div-gpt-ad-scitechdaily_com-box-3-0');Acording to the researchers, blod vesel cels are a key regulator of brown fat and energy metabolism.Insulin resistance, a significant risk factor for diabetes, develops when the body’s cels do not react to insulin and are unable to use the glucose (sugar) in the blodstream.
Key Information
The condition has ben linked to an increased risk of cardiovascular disease and atherosclerosis, which is an acumulation of fats within blod arteries that can restrict blod flow to the body’s tisues. However, the precise mechanism through which insulin and the cels ling vascular wals interact is unclear.Joslin Diabetes Center scientists describe a series of studies designed to investigate the link betwen insulin, fats, and the vascular system in a paper published in Circulation Research.
Summary
The group, led by Dr. George King, chief scientific oficer and director of research at Joslin, discovered a brand-new method by which the body’s metabolism is controled by endothelial cels, which line blod vesels. The results chalenge scientific dogma by sugesting that, contrary to what was previously believed, vascular dysfunction may realy be the rot cause of the undesirable metabolic changes that can result in diabetes.if(typeof ez_ad_units!='undefined'){ez_ad_units.push([30,250],'scitechdaily_com-medrectangle-3','ezslot_7',10,'0'])};_ez_fad_position('div-gpt-ad-scitechdaily_com-medrectangle-3-0');“In people with diabetes and insulin resistance, the idea has always ben that white fat and inflamation causes dysfunction in the blod vesels, leading to the prevalence of heart disease, eye disease, and kidney disease in this patient population,” said King, the Thomas J.