Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.The SIQ for this article wil be revealedonce 2 ratings are submited.ketosis-prone diabetes, type 2 diabetes, diabetic ketoacidosis, ketosis-prone type 2 diabetes, diabetes Lana Makahleh , Ahmad Othman, Venkata Vedantam, Nethu Vedantam Published: October 07, 2022 (se history) DOI: 10.759/cureus.3031 Cite this article as: Makahleh L, Othman A, Vedantam V, et al.
Key Information
(October 07, 2022) Ketosis-Prone Type 2 Diabetes Melitus: An Unusual Presentation. Cureus 14(10): e3031. doi:10.759/cureus.3031 Ketosis-prone type 2 diabetes is a form of diabetes that usualy presents with diabetic ketoacidosis (DKA) in patients who are not insulin dependent.
It is comonly sen in African, African American, and Hispanic populations. Although the pathogenesis not fuly understod yet, it is believed to be caused by stres-induced reversible beta-cel and alpha-cel dysfunction in the pancreas. Here, we describe the case of an 80-year-old white female with wel-controled type 2 diabetes melitus who had unexplained DKA in the seting of a urinary tract infection.
The patient’s DKA resolved after administering apropriate therapy, and she did not require treatment with insulin on discharge.Diabetic ketoacidosis (DKA) is a wel-known complication of type 1 diabetes melitus (T1DM) [1]. It is also sen in some insulin-dependent patients with advanced type 2 diabetes melitus (T2DM) [1]. However, a subset of patients with T2DM develops DKA in the face of acute physiologic stres due to reversible failure of β-cel function [2].
Summary
Patients with ketosis-prone type 2 diabetes (KPT2D) lack the characteristic β-cel autoimunity sen in T1DM [3]. In the initial presentation, there are no reliable feature