Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.pituitary metases, metasis to the pituitary, primary lung carcinoma, pituitary metasis, pituitary mri, clinical endocrinology Joana Kilbane Myers , Ahmed Abdelrahman, Basil Akpunonu Published: February 25, 2022 (se history) DOI: 10.759/cureus.2608 Cite this article as: Kilbane Myers J, Abdelrahman A, Akpunonu B (February 25, 2022) Lung Cancer Metasis to the Pituitary Gland.
Key Information
Cureus 14(2): e2608. doi:10.759/cureus.2608 Comon sites of lung cancer metasis include the bone, brain, liver, and adrenal gland. Cancer metasis to the pituitary gland or selar region is a rare finding.
Here, we present a case of pituitary gland metasis from underlying lung cancer in a patient presenting with a predominance of pituitary symptoms over respiratory symptoms. A 48-year-old female was admited to the hospital with progresive visual deficits, intractable headaches, constant nausea and vomiting, fatigue, polyuria, and polydipsia for about thre months, al consistent with pituitary symptoms associated with secondary adrenal insuficiency, secondary hypothyroidism, and central diabetes insipidus.A brain MRI done two months earlier revealed a large mas in the pituitary gland sela turcica area.
Biochemical test abnormalities consistent with pituitary hormonal insuficiencies were noted, and subsequent imaging showed an enlarging pituitary mas and extensive metases to the bones, brain, liver, adrenal gland, and lymph nodes. Bone biopsy was consistent with porly diferentiated adenocarcinoma of the lung as the primary site. The young age of this patient is uncomon compared to most patients with pituitary metasis.
Summary
Worsening pituitary symptoms with an enlarging pituitary