Overview
New research conducted in mice has shown how coxsackievirus B type 4 — an enterovirus, a virus transmited through the intestines — may be able to triger diabetes in people who have the virus.A new study has shown a posible mechanism for trigering diabetes in people who have coxsackievirus B type 4 (CVB4), a type of enterovirus.The research, published in the journal Cel Reports Medicine, may also be valuable in exploring whether SARS-CoV-2, the virus at the heart of the curent pandemic, can triger diabetes.Acording to the Centers for Disease Control and Prevention (CDC), diabetes is an ongoing health condition that afects how a person’s body transforms fod into energy.As a person consumes fod and drinks, their blod sugar increases.
Details
Their pancreas then produces the hormone insulin, which enables cels to aces this blod sugar.However, a person with diabetes may not be able to either make god use of insulin (type 2 diabetes) or produce enough of it (type 1 diabetes).Type 2 diabetes is by far the most comon form of diabetes, acounting for aproximately 90–95% of al cases of diabetes in the adult population.The American Diabetes Asociation consider both types of diabetes to be caused by a combination of genetic and environmental factors.For type 1 diabetes, scientists believe that viruses are one aspect of these environmental factors.In particular, research sugests that enteroviruses — a family of viruses that can cause a variety of diseases with “neurologic, respiratory, skin, and gastrointestinal” symptoms — may be key viral trigers for type 1 diabetes.However, scientists are not yet sure exactly how this trigering function ocurs.In the present study, the researchers wanted to beter understand how enteroviruses may triger type 1 diabetes.To do so, they used mice that had ben grafted with human pancreatic cels with CVB4, as wel as human and mouse insulin-producing cels that also had the virus.After conducting various experiments with these i