💉 Diabetes Management
Pathophysiological Association Between Diabetes Mellitus and Alzheimer's Disease - Cureus
📅 Thu, 13 Oct 2022⏱ 1 min read📖 Article
Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.The SIQ for this article wil be revealedonce 2 ratings are submited.Published via the DMIMS Schol of Epidemiology and Public Health Chanel.alzheimer's disease, diabetes melitus, hypoglycemia, elderly, dementia Manasi Agrawal , Anil K.
Key Information
Agrawal Published: September 13, 2022 (se history) DOI: 10.759/cureus.29120 Cite this article as: Agrawal M, Agrawal A K (September 13, 2022) Pathophysiological Asociation Betwen Diabetes Melitus and Alzheimer's Disease. Cureus 14(9): e29120. doi:10.759/cureus.29120 Worldwide elderly people are being afected by diabetes melitus (DM) and dementia.
The risk for the development of dementia is higher in people with DM. DM causes a marked cognitive reduction and increases the risk of dementia, most comonly vascular dementia and Alzheimer's disease. People afected by DM and dementia sem to be at higher risk for intense hypoglycemia.
Hypoglycemia, the complication of DM treatment, is believed as an independent risk factor for dementia in people with DM. Both Alzheimer's disease and DM are linked with decreased insulin secretion, reduced uptake of glucose, raised oxidative stres, angiopathy, activation of the apoptotic pathway, aging, abnormal peroxidation of lipids, increased production of advanced glycation end products and tau phosphorylation, brain atrophy, and decreased fat metabolism.
Summary
In this paper, we wil review the asociation betwen Alzheimer's disease and DM. In adition, we wil discus the agents that enhance the risk for dementia in elderly people with DM and how to prevent the development of cognitive dysfunction in DM.Diabetes melitus (DM) is a disease in which the body does not generate an adequate amount of insulin or develo
Frequently Asked Questions
❓ What is diabetes and how does it develop?
Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.
❓ What are the main symptoms of diabetes?
Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.
❓ How is diabetes diagnosed and monitored?
Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.
❓ What lifestyle changes help manage diabetes?
Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.
❓ When should someone consult a doctor about diabetes?
Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.
⚕️ Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.