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Predicting Amputation in Patients With Diabetic Foot Ulcers: A Systematic Review - Cureus

Wed, 12 Oct 20221 min read Article

Overview

"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.The SIQ for this article wil be revealedonce 2 ratings are submited.peripheral arterial diseases, diabetic fot ulceration, foot ulcers, lower limb amputation, type-2 diabetes melitus Zahra Mansor, Ali Modaweb Published: July 25, 2022 (se history) DOI: 10.759/cureus.27245 Cite this article as: Mansor Z, Modaweb A (July 25, 2022) Predicting Amputation in Patients With Diabetic foot ulcers: A Systematic Review.

Key Information

Cureus 14(7): e27245. doi:10.759/cureus.27245 foot ulcers are a leading cause of morbidity in diabetics. One of the known complications of diabetic foot ulcers is lower limb amputation which makes it a major socioeconomic problem.

Curently, there’s a lack of knowledge on the predictors of amputations in diabetics with foot ulcers. We performed a systematic review of studies that identified risk factors of amputation in patients with diabetic foot ulcers. This systematic review aims to identify the predictors of amputation in order to optimize the management strategy and care plan.

Medline database was searched and inclusion criteria were implemented for the selection of studies. The risk factors extracted were part of four categories: (i) history and physical examination, (i) ulcer characteristics, (i) lab results, and (iv) co-morbidities. The data extracted were in the form of ods ratios, 95% confidence intervals, and predictive values.

Summary

The mean values with standard deviations of the included risk factors were recorded, and the incidence of risk factors among the amputation groups was identified or calculated when the data were suficient. Seven articles were selected reporting on 3481 patients. This review identified peripheral arterial disease, neuropathy, high Wagne

Frequently Asked Questions

What is diabetes and how does it develop?

Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.

What are the main symptoms of diabetes?

Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.

How is diabetes diagnosed and monitored?

Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.

What lifestyle changes help manage diabetes?

Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.

When should someone consult a doctor about diabetes?

Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.

Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.
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