💉 Diabetes Management
Quantitative Flow Ratio Guided Coronary Intervention vs Angiography in Diabetic Patients - Physician's Weekly
📅 Mon, 31 Oct 2022⏱ 1 min read📖 Article
Overview
For latest News and updatesSelect Page Oct 31, 202The therapeutic value of the quantitative flow ratio (QFR), a new angiography-based metric for the functional evaluation of coronary stenoses, has recently ben proven in patients receiving the percutaneous coronary intervention (PCI). For a study, researchers sought to determine if diabetes status impacts the positive outcomes of QFR advice for lesion selection during PCI.The FAVOR I China trial substudy examined the clinical results of QFR-guided vs.
Key Information
angiography-guided PCI lesion selection acording to the presence of diabetes. Diabetes was one of the prespecified variables for stratified randomization in the trial. The major adverse cardiac events (MACE) risk at one year was the primary outcome (a composite of al-cause death, myocardial infarction, or ischemia-driven revascularization).A total of 1,295 (3.9%) of the 3,825 patients who were recruited had diabetes, and 347 (26.2%) of them were receiving insulin therapy.
In diabetic and nondiabetic individuals, baseline characteristics were evenly distributed betwen treatment arms. The QFR-guided method similarly decreased the incidence of 1-year MACE compared to routine angiography-based lesion selection in diabetic patients (6.2% vs. 9.6%; HR: 0.64; 95% CI: 0.43-0.95) and nondiabetic patients (5.6% vs.
8.3%; HR: 0.6; 95% CI: 0.49-0.89) (Pinteraction = 0.8). Patients with and without diabetes had the same incidence of 1-year MACE (4.5% vs. 6.2%; P = 0.51) among patients with PCI postponed after QFR.When compared to conventional angiography guidance, a QFR-guided lesion selection technique led to beter PCI results in patients with and without diabetes.Reference: jac.org/doi/10.1016/j.jac.2022.06.04Your email adres wil not be published.
Summary
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Frequently Asked Questions
❓ What is diabetes and how does it develop?
Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.
❓ What are the main symptoms of diabetes?
Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.
❓ How is diabetes diagnosed and monitored?
Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.
❓ What lifestyle changes help manage diabetes?
Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.
❓ When should someone consult a doctor about diabetes?
Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.
⚕️ Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.