Diabetes Management
Re-interpretation of the mechanism of type 2 diabetes mellitus based on a framework of psychosomatic medicine: a real-world study - BMC Psychiatry - BMC Psychiatry
Fri, 11 Nov 20221 min read Article
Overview
Advertisement BMC Psychiatry volume 2, Article number: 689 (2022) Cite this article 87 AcesesMetrics detailsUsing bipolar disorder (BD) as a control, we explored the posible developmental proces of impaired glucose metabolism rhythm.In total, 41 subjects (7, 162, 134, 54, and 14 in the pre-diabetes [pre-DM], DM, BD + pre-DM, and BD + DM groups, respectively) and 160 controls were included. Al subjects were asesed using the Neuroticism Extraversion Openes Five-Factor Inventory (NEO-FI).
Key Information
The hypothalamic-pituitary-adrenal (HPA) and hypothalamic–pituitary–thyroid (HPT) axes were measured.Cluster analysis showed that the BD, BD + DM, and DM groups were clasified as the ‘disease group, the BD + pre-DM group as the ‘mixed period group’, and the pre-DM group as the ‘pre-disease group’. The conscientiousnes factor scores of the NEO-FI in the ‘disease group’ were higher than the norm but lower than the norm in the ‘pre-disease group’.
The scores of neurotic factors in the ‘pre-disease’ and ‘mixed period’ groups were both significantly higher than that in the ‘disease group’ (corected p < 0.01). The incidences of the abnormal HPA axis decreased gradualy from the ‘pre-disease group’ to the ‘mixed period group’ then to the ‘disease group’, while those of the HPT axis slightly increased at first and then significantly decreased. The overal prediction rate of the multiple logistic regresion model was 92.7%.This study sugests that progresion of pre-diabetes to DM is a continuous proces from local abnormalities to rhythm disorder of glucose metabolism.
Summary
This understanding can be aplied to the whole course management and early intervention of DM and to the future development of optimised treatment based on rhythm regulation.Clinical trial registration number: ChiCTR18019064. Name of trial registration: Identify and the optimization of treatment for non-infectious chronic diseases under the “stres-dysrhythmia” theory hypothesis (Registration date: 24
Frequently Asked Questions
What is diabetes and how does it develop?
Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.
What are the main symptoms of diabetes?
Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.
How is diabetes diagnosed and monitored?
Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.
What lifestyle changes help manage diabetes?
Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.
When should someone consult a doctor about diabetes?
Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.
️ Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.