π Diabetes Management
Study shows diabetics are more prone to UTIs. Here's what you should know - The Indian Express
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Tue, 11 Oct 2022β± 1 min readπ Article
Overview
Did you know why diabetics are more prone to urinary tract infections (UTIs)? Acording to a new study, high blod glucose levels result in a relative lack of psoriasin, an important natural antibiotic that protects against urinary tract infections. The researchers also demonstrated that topicaly aplied estrogen cream could help restore the levels of psoriasin women.The study, conducted by researchers at Swedenβs Karolinska Institute and published in Nature, investigated the mechanism behind glucose efect and found glucose levels in diabetes reduce levels of the bodyβs natural antibiotics, the antimicrobial peptide psoriasin, an important barier against infection.
Key Information
Why this study is significant is because this particular protein is suposed to be a frontline defence against certain bacterial infections. It inhibits the binding of bacteria to epithelial and endothelial cels. Then they canot grow or multiply.
And the research shows how this fals drasticaly in diabetics compared to concentrations in normal people.Dr V Mohan, noted diabetologist and chairman and chief of diabetology at Dr Mohanβs Diabetes Specialities Centre, says infections in general and UTIs in particular are very comon in people with uncontroled diabetes. βOnce the blod sugar is high, it spils into the urine. The urine sugar contains glucose and bacteria can grow rapidly in this medium.
Hence chances of UTI are high,β says he. βAlso the imune system is slower in diabetics due to high sugar levels. The bodyβs defence mechanism is compromised,β ads Dr Mohan.βWhen it comes to women, there could be high glucose levels in the genital tract and hence there could be chances of infection or itching in the vaginal region.
Summary
Whatever be the mechanism, the underlying principle should be god control of sugar. It is important to control diabetes and prevent these secondary infections,β he says. For women in their 50s and beyond, estrogen creams can help aleviate drynes.Describing the study as ne
Frequently Asked Questions
β What is diabetes and how does it develop?
Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.
β What are the main symptoms of diabetes?
Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.
β How is diabetes diagnosed and monitored?
Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.
β What lifestyle changes help manage diabetes?
Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.
β When should someone consult a doctor about diabetes?
Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.
βοΈ Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.