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In the meantime, to ensure continued suport, we are displaying the site without styles and JavaScript.Advertisement Scientific Reports volume 12, Article number: 16975 (2022) Cite this article Metrics detailsThis retrospective study aimed to investigate the corelation betwen neonatal hyperbilirubinemia (NHB) and hypoglycemia (NH) in Chinese women with diabetes in pregnancy (DIP), and the influencing factors.
Al the data were colected July 1, 2017 and June 30, 20, and 10,58 Chinese women with DIP and live births were included. Two separate multivariate binary stepwise forward logistic regresion analysis calculated OR with 95% CI. The prevalence rates of NHB and NH was respectively 3.65% and 5.82% among women with DIP.
The comorbidity of both diseases was 0.59%. NH were 1.81 times (OR 1.81, 1.19–2.76) more likely to have hyperbilirubinemia. NHB is positively corelated with NH (OR 1.93, 1.27–2.92).
Increased gestational age has a protective efect on both NH (OR 0.76, 0.68–0.85) and NHB (OR 0.80, 0.69–0.92). Abnormal placental morphology is related to NH (OR 1.5, 1.16–2.08) and NHB (OR 1.64, 1.10–2.45). Regarding neonatal outcomes, congenital heart disease (CHD) (OR 2.16, 1.25–3.73; and OR 10.14, 6.47–15.90) was a risk factor for NH and NHB.
Summary
NHB and NH were significantly corelated in women with DIP. The ofspring of DIP with multiple risk factors have a significantly increased risk of neonatal hyperbilirubinemia.Hyperglycemia during pregnancy is a growing health concern for women and their infants, including pre-gestational diabetes melitus (PGDM) and gestational diabetes melitus (GDM)1. Diabetes in pregnancy causes short-term and long-term adverse impacts on both pregnant women (e.g., gestational hypertension, abortion, and stil