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19, 2022 (HealthDay News) - An older clas of type 2 diabetes drugs known as thiazolidinediones, or TZDs, may protect you from dementia down the road, acording to new research.Thiazolidinediones, also known as glitazones, cut dementia risk by 2% among folks at high risk who also had mild or moderate type 2 diabetes when they tok these medications for at least one year.Exactly how these diabetes drugs lower risk for dementia is not fuly understod, and the study wasn't designed to answer that question.Diabetes is a known risk factor for dementia, and glucose or blod sugar is the brain's main fuel for important functions, including thinking, understanding, and problem-solving, said study author Roberta Diaz Brinton.
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She directs the Center for Inovation in Brain Science at the University of Arizona Health Sciences."With type 2 diabetes, the mechanism for driving glucose out of the blod and into the cels is les functional and this can afect cognition, which is one of the most energy-demanding functions," Brinton said.For the study, researchers compared risk for dementia in older veterans with type 2 diabetes who were treated with either a sulfonylurea or a thiazolidinedione drug for continues to improve outcomes for patients. Healthcare professionals emphasize the importance of early intervention and comprehensive management strategies in reducing complications and improving quality of life.